Lionel Messi will miss two World Cup qualifiers after he was on Monday left out of the Argentina squad for games against Uruguay and Brazil because he reportedly suffered an injury in a club game the day before.

After missing three games for his club, Inter Miami, at the start of March with a pulled muscle, the 37-year-old Messi returned with a goal off the bench in a CONCACAF Champions Cup win. He played a full 90 minutes and scored again in an MLS win in Atlanta on Sunday but, Argentinian media reported, then felt muscle discomfort.

Argentina, the defending World Cup champions, can ensure qualification for next year’s tournament in their two games on the current international group.

They lead the 10-team South American qualifying group by five points from Uruguay and visit Montevideo on Friday before hosting Brazil in Buenos Aires on March 25.

The top six teams qualify directly for the World Cup in the United States, Mexico and Canada. The seventh-placed team is currently Bolivia with 13 points.

After 12 rounds, Messi is the top scorer in the competition with six goals.

Argentina are also without injured Roma striker Paulo Dybala and River Plate full-back Paulo Montiel.

Brazil, will be without 33-year-old Neymar, who has suffered a thigh injury and has had to postpone his return to the national team, who are fifth, seven points behind Argentina.

Squad:

Goalkeepers: Emiliano Martinez (Aston Villa, ENG), Geronimo Rulli (Marseille, FRA), Walter Benitez (PSV Eindhoven, NED).

Defenders: Nahuel Molina (Atletico Madrid, ESP), Leonardo Balerdi (Marseille, FRA), Cristian Romero (Tottenham, ENG), Nicolas Otamendi (Benfica, POR), Nicolas Tagliafico (Lyon, FRA), Facundo Medina (Lens, FRA), Juan Foyth (Villarreal, ESP), German Pezzella (River Plate)

Midfielders: Leandro Paredes (Roma, ITA), Alexis Mac Allister (Liverpool, ENG), Rodrigo De Paul (Atletico Madrid, ESP), Exequiel Palacios (Bayer Leverkusen, GER), Maximo Perrone (Como, ITA), Enzo Fernandez (Chelsea, ENG), Giuliano Simeone (Atletico Madrid, ESP), Benjamin Dominguez (Bologne, ITA), Thiago Almada (Lyon, FRA)

Forwards: Lautaro Martinez (Inter Milan, ITA), Julian Alvarez (Atletico Madrid, ESP), Angel Correa (Atletico Madrid, ESP), Nicolas Paz (Como, ITA), Santiago Castro (Bologna, ITA), Nicolas Gonzalez (Juventus, ITA).